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Main systemic delivery routes of RNA-LNPs. The selection of an appropriate route of administration may affect the efficacy of RNA medicines. RNA-LNPs are generally administered by systemic injections: (A) intramuscular (IM), (B) subcutaneous (SC), (C) intradermal (ID), (D) intravenous (IV), and (E) oral route. Created with BioRender.com.
