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. 2022 Oct 17;12(17):7203–7215. doi: 10.7150/thno.78043

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Clonogenic survival of LNCaP cells after treatment with [²²⁵Ac]Ac-mcp-M-alb-PSMA or [²²⁵Ac]Ac-mcp-D-alb-PSMA for (A) 1 h or (B) 4 h, respectively. Cells were exposed to different activity concentrations of 225Ac-labeled PSMA conjugates for the indicated treatment time and thereafter supplemented with fresh medium. Eight days later, colonies formed were stained and counted by digital analysis. Data points represent the mean colony number of three samples, normalized to values obtained for the untreated reference samples.