Table 2.
Histological comparison between cases of predominantly lobular or portal hepatitis.
| Lobular hepatitis |
Portal hepatitis |
p value | |
|---|---|---|---|
| (n = 45) | (n = 10) | ||
| Interface hepatitis | |||
| 0-1 | 23 (51%) | 2 (20%) | 0.041 |
| 2 | 13 (29%) | 4 (40%) | |
| 3 | 9 (20%) | 2 (20%) | |
| 4 | 0 | 2 (20%) | |
| Confluent necrosis | |||
| 0 | 7 (16%) | 7 (70%) | 0.009 |
| 1-2 | 12 (26%) | 2 (20%) | |
| 3-4 | 17 (38%) | 1 (10%) | |
| 5-6 | 9 (20%) | 0 | |
| Lobular necroinflammation | |||
| 0-1 | 2 (4%) | 2 (20%) | 0.004 |
| 2 | 13 (29%) | 6 (60%) | |
| 3 | 16 (36%) | 2 (20%) | |
| 4 | 14 (31%) | 0 | |
| Portal inflammation | |||
| 0-1 | 13 (29%) | 0 | 0.005 |
| 2 | 26 (58%) | 5 (50%) | |
| 3 | 6 (13%) | 5 (50%) | |
| 4 | 0 | 0 | |
| Fibrosis | |||
| 0 | 6 (13%) | 0 | 0.006 |
| 1-2 | 36 (80%) | 6 (60%) | |
| 3-4 | 3 (7%) | 3 (30%) | |
| 5-6 | 0 | 1 (10%) | |
| Inflammatory cells | |||
| Plasma cell aggregate | 28 (62%) | 8 (80%) | 0.285 |
| Eosinophil aggregate | 18 (40%) | 5 (50%) | 0.562 |
| Histological criteria | |||
| Likely | 32 (71%) | 8 (80%) | 0.572 |
| Possible | 13 (29%) | 2 (20%) | |
| Unlikely | 0 | 0 |
Histological parameters were compared between cases of lobular and portal hepatitis using the Mann-Whitney U test. A probability of p <0.05 was considered to be significant.