Table 3.
Comparison of Anorectal Manometry Findings and BET with Rectal Evacuation on Defecography in Constipated Patients (n=158)
HR-ARM parameter abnormality | Evacuation, No. | P value | Evacuation, median, % | Sensitivity, % | Specificity, % | Positive predictive value, % | Negative predictive value, % | |
---|---|---|---|---|---|---|---|---|
Normal | Reduced | |||||||
Prolonged BET | <.001 | |||||||
Normal | 88 | 20 | 78 | N/A | N/A | N/A | N/A | |
Abnormal | 21 | 29 | 18 | 59 | 81 | 58 | 81 | |
Gradient | <.001 | |||||||
Normal | 94 | 27 | 74 | N/A | N/A | N/A | N/A | |
Abnormal | 15 | 22 | 16 | 45 | 86 | 59 | 78 | |
Gradient and BET | <.001 | |||||||
Both normal | 78 | 13 | 79 | N/A | N/A | N/A | N/A | |
Either abnormal | 26 | 21 | 35 | 73 | 72 | 54 | 86 | |
Both abnormal | 5 | 15 | 3 | 31 | 95 | 75 | 75 | |
Resting anal pressure | .25 | |||||||
Normal | 100 | 42 | 70 | N/A | N/A | N/A | N/A | |
Abnormal | 9 | 7 | 33 | 14 | 92 | 44 | 70 | |
Anal squeeze increment | .73 | |||||||
Normal | 85 | 37 | 70 | N/A | N/A | N/A | N/A | |
Abnormal | 24 | 12 | 60 | 24 | 78 | 33 | 70 | |
Residual anal pressure | <.001 | |||||||
Normal | 100 | 34 | 73 | N/A | N/A | N/A | N/A | |
Abnormal | 9 | 15 | 12 | 31 | 92 | 63 | 75 | |
Rectal pressure increase | .53 | |||||||
Normal | 103 | 45 | 70 | N/A | N/A | N/A | N/A | |
Abnormal | 6 | 4 | 37 | 8 | 94 | 40 | 70 | |
Anal relaxation | .95 | |||||||
Normal | 93 | 42 | 66 | N/A | N/A | N/A | N/A | |
Abnormal | 16 | 7 | 70 | 14 | 85 | 30 | 69 | |
Urge sensation | .013 | |||||||
Normal | 101 | 40 | 70 | N/A | N/A | N/A | N/A | |
Abnormal | 5 | 8 | 3 | 17 | 95 | 62 | 72 |
Abbreviations: BE, balloon expulsion time; HR-ARM, high-resolution anorectal manometry; N/A, not applicable.
Incomplete rectal evacuation was defined as <25%. Prolonged BET was defined as >60 seconds.