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. Author manuscript; available in PMC: 2023 Nov 22.
Published in final edited form as: Biomater Sci. 2022 Nov 22;10(23):6688–6697. doi: 10.1039/d2bm00415a

Figure 2: In vitro cellular responses to paKG NPs + MTX.

Figure 2:

(a-h) Flow cytometry of in vitro splenic T cell responses treated with a final well concentration of 1 mg/mL of methotrexate and/or 0.1 mg/mL of paKG nanoparticles and cultured in 37°C for 48-72 hrs (negative control = No treatment), (a-c) in the absence and, (d-g) presence of a final well concentration of 2.5 μg/mL of Concanavalin A (ConA – used to mimic inflammation in vitro) (n = 4-6; avg ± SEM; * = p ≤ 0.05; One-Way ANOVA, Brown-Forsythe and Welch ANOVA tests, unpaired t with Welch’s correction).