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. 2022 Nov 11;9:993097. doi: 10.3389/fcvm.2022.993097

Table 1.

Characteristics of the study participants.

Variables Total RC Quartiles, mmol/L P-value
(< 0.41) (0.41–0.56) (0.56–0.74) (≥0.74)
N 8,028 2,006 2,005 1,988 2,029
Male, n (%) 2,938 (36.60) 638 (31.80) 726 (36.21) 714 (35.92) 860 (42.39) <0.001
Age, years 56.57 ± 9.04 55.81 ± 9.34 56.87 ± 9.51 57.17 ± 8.73 56.44 ± 8.49 <0.001
BMI, kg/m2 25.93 ± 3.42 24.49 ± 3.18 25.74 ± 3.39 26.52 ± 3.42 26.99 ± 3.16 <0.001
baPWV, cm/s 1646.85 ± 374.11 1566.06 ± 373.14 1629.54 ± 355.96 1679.02 ± 380.17 1712.30 ± 370.73 <0.001
RC, mmol/L 0.56 (0.41–0.74) 0.32 (0.25–0.36) 0.48 (0.44–0.52) 0.63 (0.59–0.68) 0.91 (0.81–1.10) <0.001
TC, mmol/L 5.35 ± 0.98 4.75 ± 0.76 5.14 ± 0.82 5.52 ± 0.84 5.97 ± 1.04 <0.001
TG, mmol/L 1.28 (0.91–1.83) 0.80 (0.65–0.99) 1.13 (0.91–1.34) 1.49 (1.20–1.80) 2.36 (1.82–3.09) <0.001
HDL-C, mmol/L 1.44 ± 0.38 1.71 ± 0.38 1.49 ± 0.34 1.37 ± 0.31 1.20 ± 0.28 <0.001
LDL-C, mmol/L 3.28 ± 0.82 2.74 ± 0.61 3.17 ± 0.65 3.51 ± 0.69 3.70 ± 0.95 <0.001
Non-HDL-C, mmol/L 3.90 ± 0.98 3.04 ± 0.64 3.65 ± 0.66 4.15 ± 0.70 4.77 ± 0.94 <0.001
eGFR, ml/min per 1.73 m2 94.96 ± 13.01 96.94 ± 12.21 94.90 ± 13.08 94.11 ± 13.11 93.90 ± 13.38 <0.001
Smoking, n (%) 1,574 (19.61) 264 (13.16) 350 (17.46) 385 (19.37) 575 (28.34) <0.001
Drinking, n (%) 1,921 (23.94) 414 (20.65) 463 (23.09) 478 (24.06) 566 (27.91) <0.001
Hypertension, n (%) 3,693 (46.00) 741 (36.94) 899 (44.84) 961 (48.34) 1,092 (53.82) <0.001
Diabetes, n (%) 1,864 (23.22) 335 (16.70) 401 (20.00) 486 (24.45) 642 (31.64) <0.001
Self-reported MI, n (%) 70 (0.87) 8 (0.40) 15 (0.75) 23 (1.16) 24 (1.18) <0.001
Self-reported Stroke, n (%) 272 (3.39) 58 (2.89) 87 (4.34) 69 (3.47) 58 (2.86) <0.001

Continuous variables are presented as median (interquartile range) or mean ± standard deviation, and dichotomous variables are presented as frequency (percentage).

Q, quartile; BMI, body mass index; eGFR, estimated glomerular filtration rate; MI, myocardial infarction; baPWV, brachial-ankle pulse wave velocity; TC, total cholesterol; TG, triglyceride; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; RC, remnant cholesterol.