Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2022 Nov 24;12:20247. doi: 10.1038/s41598-022-24292-5

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Results of the western blot assays. (A) Phospho-tau/tau ratio. ‘Old rats’ column: §:p = 0.016 significant difference vs control ((Mann–Whitney U-test U = 18; because of variance inhomogeneity non-parametric test was used), effect size: 1.23. Group size of old STZ-treated rats: n = 9. (B) β-amyloid level ns. Group size of old STZ-treated rats: n = 10. (C) Comparison of tissue protein levels of β-amyloid in 5 month old (young naïve), 12 month old (young experienced) and 25 month old (old experienced) rats measured by western blot. Means ± SEM values are shown. *, ***: p < 0.05, p < 0.001 significant difference vs. young naïve rats, #: p < 0.05 significant difference vs. young experienced rats (post-hoc Duncan test following one way ANOVA (F(2, 24) = 10.09, p = 0.001). Group sizes are 9, 11 and 11 for young naïve (y.n.), young experienced (y.e.) and old experienced rats (o.e.), respectively. The inset shows representative blots; original complete blots are presented in Supplementary material, Figs. S2-S3.