Table 2.

Maternal, fetal, and placental weights and demographics.

Characteristic	Control	THC	p-value
N	5	5
Maternal age (years)	10.0 ± 2.3	9.9 ± 2.1	0.945
Parity	3.6 ± 0.5	2.2 ± 2.2	0.226
Maternal weight at G60 days (kg)	7.53 ± 1.02	7.74 ± 0.47	0.692
Maternal weight at G155 days (kg)	8.94 ± 1.20	8.95 ± 0.48	0.990
Total placental weight (g)	105.2 ± 17.6	105.0 ± 18.7	0.984
Fetal measurements
Fetal sex (male:female)	2:3	3:2	–
Fetal birth weight (kg)	0.48 ± 0.08	0.46 ± 0.07	0.676
CRL (cm)	19.12 ± 1.20	19.32 ± 2.08	0.859
Right foot (cm)	7.62 ± 0.66	7.3 ± 0.56	0.434
AC (cm)	19.32 ± 2.08	11.92 ± 1.57	0.930
HC (cm)	17.18 ± 4.84	19.04 ± 0.98	0.444
Brain (g)	53.28 ± 2.71	51.92 ± 1.69	0.373
Thymus (g)	1.92 ± 0.59	1.45 ± 0.37	0.177
Thyroid (g)	0.35 ± 0.10	0.20 ± 0.09	0.067
Adrenals (g)	0.26 ± 0.04	0.29 ± 0.13	0.598
Pituitary (g)	0.01 ± 0.01	0.02 ± 0.01	0.683
Ovaries (g)	0.09 ± 0.01 (n = 3)	0.09 ± 0.08 (n = 2)	0.981
Testes (g)*	0.13 ± 0.10 (n = 2)	0.06 ± 0.03 (n = 3)	< 0.05
Kidneys (g)	2.14 ± 0.31	2.18 ± 0.23	0.875
Pancreas (g)	0.35 ± 0.07	0.39 ± 0.18	0.643
Liver (g)	12.00 ± 2.23	12.32 ± 2.39	0.831
Lungs (g)	9.45 ± 2.76	9.07 ± 3.16	0.845
Spleen (g)	0.73 ± 0.17	0.57 ± 0.23	0.249
Heart (g)	2.84 ± 0.47	2.38 ± 0.62	0.222
Body weight (g)	484.36 ± 76.51	463.71 ± 71.21	0.670
Heart to weight ratio*	0.0058 ± 0.0005	0.0051 ± 0.0006	< 0.05

CRL crown rump length, AC abdominal circumference, HC head circumference.

Tissue to fetal body weight ratio was not significant for all tissues except heart.

Data are means ± SD. Statistical analysis performed using Welch’s t-test.

*p < 0.05.