Table 2.
Inhibitory role of different tropical plant extracts against dipeptidyl peptidase-IV enzyme.
| Plant | Family | Part used in the investigation | Organic solvent | IC50 value/percentage inhibition | Extraction method | References |
|---|---|---|---|---|---|---|
| Urena lobata | Malvaceae | Root | Water Ethanol |
6,489.88 µg/ml 1,654.64 µg/ml |
Decoction | (78) |
| Pueraria tuberose | Fabaceae | Root | Water Methanol |
17.4 mg/ml Activity is reduced in a time-dependent manner |
Decoction Continuous soxhlet |
(84, 102) |
| Withania coagulans | Solanacea | Root | Methanol (80%, 100%) Ethanol |
8.76 µg/ml 21.03 µg/ml |
Hot percolation | (86, 103) |
| Ferrula asafetida | Umbelliferae | Seed | Methanol Ethanol Water Methanol–ethanol |
24% | Percolation | (45) |
| Desmodium gangeticum | Leguminosae | Aerial parts | Water | 255.5 µg/ml | Maceration | (92) |
| Moringa oleifera | Moringaceae | Leaf | Ethanol Ethyl acetate Hexane Aqueous |
798 nm | Percolation | (93, 94) |
| Morus alba | Moraceae | Stem bark | Methanol | 23% | MAE | (96) |
| Pterocarpus marsupium | Leguminosae | Root Stem Leaf |
Petroleum ether Methanol Ethyl acetate Chloroform |
273.73 µg/ml | Soxhlet and maceration | (32) |
| Curcligo latifolia | Hypoxidaceae | Root Fruit |
Methanol Ethanol Acetonitrile |
7.02% to 66.15% 2.69% to 42.79% (increased with respect to concentration dependent) |
Subcritical water extraction | (104) |
| Melicope latifolia | Rutaceae | Bark | Methanol Chloroform Hexane |
990.21 µg/ml 221.58 µg/ml 5,872.03 µg/ml |
Maceration | (105) |