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. 2022 Nov 11;13:1053819. doi: 10.3389/fimmu.2022.1053819

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Copyright © 2022 Wei, Dong, Bi, Chen, Huang, Li, Liu, Fu and Yang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Single-cell RNA-sequencing analysis identifies maternal fetal interface marker genes (A) Flowchart depicting the overall design of the single-cell RNA-sequencing analysis. (B) t-SNE plot of 112528 cells from five normal samples and three RM samples. dM, decidual macrophages; dNK, decidual NK cells; DSC, decidual stromal cells; EVT, extravillous trophoblast; VCT, villous cytotrophoblast; Mo, Monocytes; Endo, endothelial cells; SCT, syncytiotrophoblast; DC, dendritic cells; RBC, red blood cells; PV, perivascular cells; Epi, epithelial glandular cells; F, fibroblasts. (C) Dotplot map showing the expression of classical cell type‐specific marker genes in each cluster. (D) t-SNE plot of the five main immune cell types. (E) t-SNE plot showing the expression of the marker genes of the five cell types noted above.