Table 3.
Identification of RM drug candidates.
| Drug | P-value | Odds Ratio | Combined Score | Drug Targets |
|---|---|---|---|---|
| Irinotecan | 4.88E-04 | 19.68980021 | 150.1446587 | MBNL2;TBC1D12;PUM1;CD2AP |
| Alsterpaullone | 0.011055064 | 9.478342428 | 42.69866877 | MBNL2;TBC1D12;PUM1 |
| Camptothecin | 0.011584032 | 9.306841046 | 41.49108607 | MBNL2;TBC1D12;PUM1 |
| Chlorzoxazone | 0.007629886 | 10.93725643 | 53.32658862 | ACTR2;RPN2;PUM1 |
| GW-8510 | 0.007696558 | 10.9009324 | 53.05464254 | MBNL2;TBC1D12;PUM1 |
| POTASSIUM | 0.022293962 | 7.162796834 | 27.24326379 | MBNL2;TBC1D12;CD2AP |
| (-)-Epigallocatechin | 0.029804748 | 6.349786932 | 22.3073575 | MBNL2;TBC1D12;CD2AP |
| Verteporfin | 0.003997787 | 28.05978648 | 154.9465424 | NCSTN;RPN2 |
| Strophanthidin | 0.005850578 | 22.98362573 | 118.1637568 | ACTR2;PUM1 |
| Uranium | 0.002989614 | 32.64628099 | 189.7601315 | ACTR2;PUM1 |
| Azacitidine | 0.016801262 | 13.08600337 | 53.47335226 | TBC1D12;PUM1 |
| Etifenin | 0.017560467 | 12.77495881 | 51.63772641 | ACTR2;PUM1 |
| Staurosporine | 0.019811159 | 11.96043277 | 46.90295556 | TBC1D12;PUM1 |
| Neostigmine | 0.019868958 | 11.94135802 | 46.79336577 | ACTR2;PUM1 |
| Meclofenoxate | 0.023657885 | 10.84781997 | 40.61487591 | ACTR2;NCSTN |
| Captopril | 0.033293867 | 8.96440281 | 30.5003233 | ACTR2;PUM1 |
| Tyrphostin | 0.010353604 | 16.98521739 | 77.62958757 | TBC1D12;PUM1 |