TABLE 4.
Associations between cannabis use and FA of the cingulum and ATR.
| Cingulum | ATR | |||||
|
|
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| F | df | p | F | df | p | |
| Age 20 FA• | ||||||
| Adolescent cannabis use group | 3.83 | 2 | 0.023 | 6.41 | 2 | 0.002 |
| Hemisphere | 11.83 | 1 | < 0.001 | 15.88 | 1 | < 0.001 |
| Head motion | 5.07 | 1 | 0.025 | 0.49 | 1 | 0.483 |
| Change in FA from 20 to 22•• | ||||||
| Extended cannabis use group | 4.43 | 2 | 0.013 | 3.48 | 2 | 0.032 |
| Hemisphere | 15.52 | 1 | < 0.001 | 2.64 | 1 | 0.105 |
| Head motion (age 20) | 3.08 | 1 | 0.08 | 1.53 | 1 | 0.217 |
| Head motion (age 22) | 1.96 | 1 | 0.162 | 1.38 | 1 | 0.242 |
Each quadrant represents one ANCOVA and significant associations (p < 0.025) are bolded. Trend level findings are italicized. •dferror = 311, dftotal = 316; ••dferror = 310, dftotal = 316. Change in FA from 20 to 22 represents the difference score for FA from age 20 to 22. FA, fractional anisotropy; ATR, anterior thalamic radiations; df, degrees of freedom.