TABLE 6.
Sensitivity analyses for alcohol exposure.
| Cingulum | ATR | |||||
|
|
|
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| F | df | p | F | df | p | |
| Results controlling for alcohol exposure | ||||||
| Age 20 FA• | ||||||
| Adolescent cannabis use group | 7.85 | 2 | <0.001 | 8.38 | 2 | <0.001 |
| Hemisphere | 11.69 | 1 | <0.001 | 14.53 | 1 | <0.001 |
| Head motion (age 20) | 7.01 | 1 | 0.009 | 0.37 | 1 | 0.541 |
| Cumulative alcohol exposure (age 13–19) | 13.51 | 1 | <0.001 | 0.65 | 1 | 0.422 |
| Change in FA from 20 to 22•• | ||||||
| Extended cannabis use group | 4.63 | 2 | 0.01 | 2.53 | 2 | 0.082 |
| Hemisphere | 15.5 | 1 | <0.001 | 2.64 | 1 | 0.105 |
| Head motion (age 20) | 3.41 | 1 | 0.066 | 1.41 | 1 | 0.235 |
| Head motion (age 22) | 2.23 | 1 | 0.136 | 1.27 | 1 | 0.26 |
| Cumulative alcohol exposure (age 13–21) | 0.66 | 1 | 0.417 | 0.07 | 1 | 0.791 |
Each quadrant represents one ANCOVA and significant associations (p < 0.025) are bolded. Associations that only reach trend-level significance after accounting for alcohol exposure are italicized. •dferror = 298, dftotal = 304; ••dferror = 309, dftotal = 316. Change in FA from 20 to 22 represents the difference score for FA from age 20 to 22. FA, fractional anisotropy; ATR, anterior thalamic radiations; df, degrees of freedom.