Table 2. Diuretics used on the First Day of Trial Drug Administration.

Item/category	Tolvaptan (N = 46)	Placebo (N = 45)	p value
Use of diuretic			0.6216
Loop diuretic alone	21 (45.7%)	18 (40.0%)
Loop + Spironolactone	19 (41.3%)	24 (53.3%)
Loop + Spironolactone + Thiazide	3 (6.5%)	2 (4.4%)
Loop + Thiazide	3 (6.5%)	1 (2.2%)
Dose of loop diuretic*			0.3585
< 40 mg/day	6 (13.0%)	9 (20.0%)
40 mg/day-80 mg/day	36 (78.3%)	29 (64.4%)
≥ 80 mg/day	4 (8.7%)	7 (15.6%)

* Flurosemide oral form equivalence.