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Table 1. Functional and cardiopulmonary exercise test (CPET) parameters in risk assessment.

Low risk (< 5%) Intermediate risk (5-10%) High risk (> 10%)
WHO functional class I, II III IV
6MWD > 440 m 165-440 m < 165 m
CPET parameters
 Peak VO2, mL·kg-1·min-1 > 15 44880 < 11
 Peak VO2, % predicted > 65 65-35 < 35
 VE/VCO2 slope < 36 36-45 > 45

6MWD, 6-minute walking distance; VO2, oxygen uptake; VCO2, carbon dioxide production; VE, minute ventilation; VE/VCO2 slope, slope of the relationship between VE and VCO2.