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. 2022 Nov 11;27(22):7774. doi: 10.3390/molecules27227774

Figure 7.

Figure 7

DHTS inhibits tumor growth in OXA-resistant HCT116 CRC mice model. (A) Tumor size in nude mice at the end of the study; (B) body weight growth curve of nude mice; (C) tumor weight in nude mice at the end of the study; (D) tumor growth curve in nude mice; (E) H&E staining of heart, liver, spleen, lung, and kidney in nude mice; (F,G) IHC staining and analysis of H&E, TUNEL, and Ki67 in mouse tumors (compared to the control group, * p < 0.05, *** p < 0.001). The red circle represents the area of necrosis in the tumor, and the red arrow indicates positive for Tunel and Ki67 staining.