Table 1.
Demographic and clinical characteristics of child study participants in the VDAART discovery population and COPSAC replication population.
| Discovery Cohort: VDAART | ||
|---|---|---|
| Number of subjects | Age 1 Year (n = 449) | Age 6 Years (n = 421) |
| BMI kg/m2, mean (SD) | 17.4 (2.2) | 16.9 (2.8) |
| Sex, n (%) | ||
| Female | 205 (45.7) | 192 (45.6) |
| Male | 244 (54.3) | 229 (54.4) |
| Race, n (%) | ||
| Black | 220 (49.0) | 207 (49.2) |
| White | 143 (31.8) | 133 (31.6) |
| Other | 86 (19.2) | 81 (19.2) |
| Ethnicity, n (%) | ||
| Hispanic or Latino | 159 (35.4) | 146 (34.7) |
| Not Hispanic or Latino | 290 (64.6) | 275 (65.3) |
| Study site, n (%) | ||
| Boston | 139 (31.0) | 123 (29.2) |
| San Diego | 149 (33.2) | 144 (34.2) |
| St. Louis | 161 (35.9) | 154 (36.6) |
| Oral/Inhaled Corticosteroid Use, n (%) | 40 (8.9) | 115 (27.3) |
| Asthma Diagnosis by Age 6, n (%) | 121 (26.9) | 106 (25.2) |
| Total Infection Count to Age 6, mean (SD) | 28.3 (13.3) | 28.3 (12.9) |
| Replication cohort: COPSAC | ||
| Number of subjects | Age 18 Mos. (n = 494) | Age 6 Years (n = 481) |
| BMI kg/m2, mean (SD) | 16.4 (2.2) | 15.4 (1.3) |
| Sex, n (%) | ||
| Female | 240 (48.6) | 224 (46.6) |
| Male | 254 (51.4) | 257 (53.4) |
| Oral/Inhaled Corticosteroid Use, n (%) | 76 (15.4) | 153 (31.8) |
| Asthma Diagnosis by Age 6, n (%) | 119 (24.1) | 105 (21.8) |
| Total Infection Count to Age 3, mean (SD) | 15.2 (9.0) | 14.9 (9.2) |