Table 3.
Clinical presentation and outcomes in elderly patients hospitalized with COVID-19 and adult patients.
| Variables * | <70 Years (n = 234) | ≥70 Years (n = 360) | p-Value |
|---|---|---|---|
| Number of signs and symptoms at admission | 0.010 | ||
| 0 | 9 (3.8%) | 36 (10.0%) | |
| 1 | 34 (14.5%) | 50 (13.9%) | |
| 2 | 97 (41.5%) | 163 (45.3%) | |
| ≥3 | 94 (40.2%) | 111 (30.8%) | |
| Clinical signs and symptoms | |||
| Digestive symptoms | 20 (8.5%) | 59 (16.4%) | 0.005 |
| Anosmia | 42 (17.9%) | 55 (15.3%) | 0.389 |
| Ageusia | 58 (24.8%) | 74 (20.6%) | 0.225 |
| Fatigue | 16 (69.7%) | 267 (74.2%) | 0.229 |
| Dyspnea | 24 (10.3%) | 61 (16.9%) | 0.022 |
| Confusion | 11 (4.7%) | 38 (10.6%) | 0.011 |
| Headache | 23 (9.8%) | 44 (12.2%) | 0.367 |
| Fever | 177 (75.6%) | 238 (66.1%) | 0.013 |
| Cough | 153 (65.4%) | 255 (70.8%) | 0.161 |
| COVID-19 Outcomes | |||
| Severe COVID-19 | 29 (12.4%) | 71 (19.7%) | 0.019 |
| Severe imaging features | 37 (15.8%) | 83 (23.1%) | 0.031 |
| Mean duration of hospital stay | 12.7 ± 3.3 | 14.1 ± 4.0 | <0.001 |
| Median duration from symptom onset until hospital admission | 4.5 (6.5) | 3.5 (3.0) | <0.001 |
| Viral clearance | 12 (9) | 14 (12) | <0.001 |
| ICU admissions | 18 (7.7%) | 53 (14.7%) | 0.009 |
| Median duration from hospital admission to ICU admission | 5.0 (7.0) | 3.5 (3.0) | <0.001 |
| SOFA score | 4.4 (3.1) | 6.5 (4.8) | <0.001 |
| Median duration of ICU stay | 7.3 (6.6) | 5.6 (4.9) | <0.001 |
| Severe in-hospital complications | 24 (10.3%) | 59 (16.4%) | 0.035 |
| Intubation | 11 (4.7%) | 34 (9.4%) | 0.032 |
| Oxygen supplementation | 86 (36.8%) | 159 (44.2%) | 0.072 |
| Mortality | 8 (3.4%) | 27 (7.5%) | 0.039 |
* Data reported as n (%) and calculated using the Chi-square test and Fisher’s exact test unless specified differently; BMI—Body Mass Index; ICU—Intensive Care Unit; SOFA—Sequential Organ Failure Assessment.