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. 2022 Nov 18;23(22):14362. doi: 10.3390/ijms232214362

Table 1.

Elemental concentrations in sera of BD patients before and after treatment.

Element Element Concentration
Before Treatment SD After
Treatment
SD Sum of Positive Ranks Sum of Negative Ranks Statistics
p
B (µg/L) 58 36 63 59 39 −27 0.311
Ba (µg/L) 2.73 0.98 2.92 0.83 28.5 −26.5 0.469
Ca (mg/L) 136 8.49 134 5.06 22 −33 0.303
Co (µg/L) 0.65 0.32 0.63 0.34 12.5 −15.5 0.492
Cr (µg/L) 6.01 4.73 3.93 2.20 17 −49 0.087
Cu (mg/L) 1.61 0.17 1.51 0.25 6.5 −29.5 0.054
Fe (mg/L) 6.6 5.5 14 24.83 29 −26 0.460
K (mg/L) 764 479 898 562.4 35 −31 0.449
Li (mg/L) 22 9.3 18 4.48 23.5 −42.5 0.215
Mg (mg/L) 33 3.49 33 4.38 30.5 −35.5 0.429
Mn (µg/L) 5.91 8.25 2.24 1.28 26 −40 0.287
Na (%) 0.43 0.02 0.42 0.03 13.5 −41.5 0.085
Ni (µg/L) 6.69 7.79 4.57 2.35 28 −27 0.490
Pb (µg/L) 0.60 0.55 0.76 0.66 25 −11 0.203
PO4 (mg/L) 718 310 794 288.2 44 −22 0.182
Rb (mg/L) 0.77 0.49 0.89 0.54 34 −32 0.482
SO4 (%) 0.50 0.05 0.49 0.03 20.5 −34.5 0.254
Sr (µg/L) 47 11.22 49 11.29 36 −9 0.062
V (µg/L) 1.69 2.46 0.63 0.36 9 −46 0.034 *
Zn (mg/L) 1.22 0.28 1.40 0.90 29.5 −36.5 0.389

Metals were extracted and determined in sera samples (n = 11 except B and Pb in which n = 8 and 9, respectively), as described in the materials and methods. * The effect of the treatment was analyzed utilizing nonparametric Exact One-tail Wilcoxon Signed-Ranks Test.