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. 2022 Nov 3;14(11):2370. doi: 10.3390/pharmaceutics14112370

Table 1.

bEVs involved in the pathogenic infections and their roles.

Origin of bEV Infecting Pathogens Role of bEV Reference
Gram-positive bacteria
Bifidobacterium longum Food-borne infections Induction of progenitor cells [96]
Burkholderia spp. Activity against A. baumannii and S. aureus N.D. [97]
L. gasseri Human Immunodeficiency Virus (HIV) Change in susceptibility pattern of viral infection by regulation of toll-like receptor (TLR)-2 signaling [98]
L. rhamnosus Superficial infections M2 Macrophage [99]
S. aureus Pneumococcal infection TH1-mediated cell immunity [100]
Streptococcus spp. Streptococcal infection Induction of dendritic cells [101]
Tetragenococcus halophilus Opportunistic pathogens Anti-inflammatory factor interferon beta (IFN-β) [102]
Gram-negative bacteria
Acinetobacter spp. Pan-drug resistant A. baumannii Activation of IgG and IgM [103]
Borrelia burgdorferi B. burgdorferi colonization Stabilizing superoxide [104]
Helicobacter pylori H. pylori infection Induction of TH2 immune cells [105]
K. pneumoniae K. pneumoniae infection Humoral and cellular immunity [106]
N. meningitis Meningococcal disease IgG-mediated response [107]
Pertussis A Bordetella pertussis infection Induction of CD4 cells [108]
P. aeruginosa Lethal dose of P. aeruginosa Mixed cellular response [109]