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CLSM analysis of T. pyogenes (BMH06-3) biofilm on the silicon hydrogel lenses after the in vivo treatment of luteolin (Green: live bacteria; red: killed bacteria; black: no bacteria). (a) Blank control biofilm. (b) Ceftiofur group (1.5 mg/kg b.w). (c–e) Luteolin group (50 mg/kg b.w; 100 mg/kg b.w; 150 mg/kg b.w).
