Table 2.
Computational analysis for a subset of HaCaT keratinocyte-expressed thermostable proteins also found widely expressed in other cell types (see also Figure 6). Columns as in Table 1.
| Protein | UniProt # | AA | Protein Role | PONDR-FIT (0–1) |
RAPID Disorder % |
SLIDER IDR (0–1) | catGRAN a |
|---|---|---|---|---|---|---|---|
| Prelamin A/C | P02545 | 664 | Nuclear membrane support, scaffolding | 0.620 | 34.79 | 0.9015 | 0.904 |
| TAB182 | Q9C0C2 | 1729 | Nuclear and cyto-plasmic RNA-binding | 0.734 | 51.13 | 0.9281 | 1.975 |
| Calpastatin | P20810 | 708 | Calpain protease inhibitor | 0.804 | 78.39 | 0.9565 | 1.010 |
| SERBP1 | Q8NC51 | 408 | mRNA stability, PML formation | 0.751 | 60.54 | 0.9049 | 2.829 |
| Nucleolin 1 | P19338 | 710 | RNA-binding, pre-rRNA transcription | 0.633 | 62.39 | 0.9357 | 2.495 |
| ADIRF | Q15847 | 76 | Transcription factor | 0.810 | 50.00 | 0.6675 | −0.330 |
a catGRAN, catGRANULE Propensity, for relative scoring, see Section 3. AA, amino acids. TAB182, 182 kDa tankyrase-1-binding protein. SERBP1, SERPINE1 mRNA-binding protein 1 (alias, Plasminogen activator inhibitor 1 RNA-binding protein). ADIRF, adipogenesis regulatory factor.