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. 2022 Nov 17;23(22):14253. doi: 10.3390/ijms232214253

Table 3.

Angiogenic processes regulated by TRPM subunits and TRPA1.

TRP Subunit Angiogenic Processes Regulated
TRPM2 Migration in vitro, neovascularization in vivo.
TRPM4 Negative regulation of in vitro tubulogenesis and in vivo angiogenesis; supports H2O2-induced migration.
TRPM7 Negative regulation of HUVEC proliferation, adhesion, and migration in vitro and tubulogenesis in vivo; positive regulation of HMEC proliferation and migration.
TRPA1 Tube formation in vitro and neovascularization upon corneal cauterization in vivo.