Table 3.
TRP Subunit | Angiogenic Processes Regulated |
---|---|
TRPM2 | Migration in vitro, neovascularization in vivo. |
TRPM4 | Negative regulation of in vitro tubulogenesis and in vivo angiogenesis; supports H2O2-induced migration. |
TRPM7 | Negative regulation of HUVEC proliferation, adhesion, and migration in vitro and tubulogenesis in vivo; positive regulation of HMEC proliferation and migration. |
TRPA1 | Tube formation in vitro and neovascularization upon corneal cauterization in vivo. |