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(a) The uterine slices after application into the vaginal collar of an extracorporeally perfused human uterus of radiolabeled progesterone (3H-P), used as a test substance, and 14C butanol, used as free diffusible reference substance, to calculate the P uterine pharmacokinetics and metabolism of the uterus; (b) The uptake of progesterone into the myometrium and endometrium after radiolabeled vaginal P application by autoradiography.
