Table 3.
Predictors of the lethal outcome in CDI before COVID-19.
| Risk Factors | p | Odds Ratio | 95% C.I. for Odds Ratio | |
|---|---|---|---|---|
| Lower | Upper | |||
| Diabetes mellitus | 0.820 | 0.833 | 0.173 | 4.010 |
| Charlson comorbidity score | 0.356 | 0.754 | 0.414 | 1.373 |
| Number of antibiotics used before CDI onset | 0.717 | 1.258 | 0.364 | 4.349 |
| Cephalosporins of the third generations before CDI onset | 0.993 | 1.009 | 0.136 | 7.459 |
| Fluoroquinolones before CDI onset | 0.485 | 0.552 | 0.104 | 2.935 |
| CRP | <0.001 | 1.033 | 1.017 | 1.049 |
| Corticosteroids before CDI onset | 0.575 | 1.630 | 0.295 | 9.020 |
| Concomitant antibiotic therapy | 0.996 | <0.001 | <0.001 | . |
| Without concomitant therapy | 0.998 | <0.001 | <0.001 | . |
| WBC more than 15 × 109/L | 0.528 | 2.380 | 0.161 | 35.173 |
| Albumin less than 25 g/L | 0.727 | 0.765 | 0.169 | 3.456 |
| Concomitant PPI therapy | 0.609 | 0.683 | 0.159 | 2.939 |
CDI: Clostridium difficile infection; COVID-19 (Coronavirus disease 2019); C.I.: confidence interval; PPI: proton pump inhibitors; CRP: C-reactive protein; WBC—white blood cells.