Table 2.
Effects of TCI227 on the weights of organs, adipose tissues, and muscle tissues in PO-induced hyperuricemia SD rats.
| Weight of Organs and Tissues (mg/g rat) |
Control | HC | HC + LD | HC + MD | HC + HD | HC + AP |
|---|---|---|---|---|---|---|
| Liver | 33.62 ± 1.74 | 38.56 ± 1.57 ## | 38.29 ± 2.07 | 38.79 ± 2.47 | 37.08 ± 2.33 | 37.06 ± 2.19 |
| Heart | 3.53 ± 0.18 | 3.54 ± 0.26 | 3.58 ± 0.25 | 3.48 ± 0.30 | 3.49 ± 0.38 | 3.41 ± 0.23 |
| Lung | 3.72 ± 0.32 | 3.99 ± 0.23 | 3.82 ± 0.37 | 3.83 ± 0.19 | 4.04 ± 0.19 | 4.05 ± 0.40 |
| Spleen | 2.36 ± 0.92 | 5.66 ± 1.00 ## | 6.52 ± 0.81 | 5.78 ± 1.05 | 5.27 ± 1.14 | 5.52 ± 1.14 |
| Kidney | 8.43 ± 1.00 | 8.51 ± 0.49 | 8.45 ± 0.64 | 9.00 ± 0.48 | 8.49 ± 0.89 | 8.11 ± 0.38 |
| Epididymal adipose tissue | 8.89 ± 1.67 | 7.52 ± 1.64 | 8.51 ± 1.95 | 6.97 ± 1.49 | 7.83 ± 1.62 | 6.77 ± 3.16 |
| Perirenal adipose tissue | 11.05 ± 3.04 | 7.52 ± 2.25 # | 8.87 ± 3.39 | 7.31 ± 1.58 | 8.02 ± 2.62 | 7.39 ± 1.46 |
| Mesenteric adipose tissue | 6.00 ± 2.21 | 7.44 ± 2.68 | 10.12 ± 2.83 | 10.31 ± 5.75 | 9.05 ± 3.26 | 7.69 ± 2.21 |
| Subcutaneous adipose tissue | 13.28 ± 2.94 | 11.07 ± 2.98 | 12.74 ± 3.32 | 11.50 ± 1.90 | 12.75 ± 1.94 | 9.44 ± 1.76 |
| Brown adipose tissue | 0.64 ± 0.20 | 0.52 ± 0.10 | 0.45 ± 0.22 | 0.61 ± 0.28 | 0.49 ± 0.16 | 0.58 ± 0.17 |
| Gastrocnemius muscle | 7.87 ± 2.83 | 9.21 ± 2.49 | 9.14 ± 2.67 | 8.71 ± 2.66 | 9.11 ± 2.85 | 9.16 ± 2.38 |
| Soleus muscle | 0.92 ± 0.14 | 0.84 ± 0.08 | 0.84 ± 0.10 | 0.83 ± 0.11 | 0.90 ± 0.09 | 0.91 ± 0.07 |
The reported values are means ± SD (n = 8); # significantly differs from the HC group (p < 0.05); ## significantly differs from the HC group (p < 0.01).