Table 1.
The enriched metabolic pathways associated with MAFLD (metabolomics).
| Metabolic Pathway | Significant Overlap 1 | Adj. p-Value 2 | Biological Process |
|---|---|---|---|
| Tyrosine metabolism | 5 | 1.87 × 10−3 | Amino acid metabolism |
| Linoleate metabolism | 5 | 4.86 × 10−4 | Lipid metabolism |
| Fatty acid activation | 4 | 5.26 × 10−4 | |
| Fatty acid Metabolism | 3 | 6.15 × 10−4 | |
| De novo fatty acid biosynthesis | 4 | 6.20 × 10−4 | |
| Purine metabolism | 3 | 8.29 × 10−4 | Nucleotide metabolism |
| Glycosphingolipid metabolism | 3 | 6.31 × 10−4 | Phospholipid metabolism |
| Glycerophospholipid metabolism | 3 | 4.54 × 10−3 |
1 Number of significant metabolites; 2 the adjusted p-Values were calculated to estimate the false discovery rate. Pathways with ≥3 significant metabolites and FDRs of <25% were considered.