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. 2022 Nov 13;14(22):4803. doi: 10.3390/nu14224803

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Altered levels of leptin, progranulin, and resistin in SPG11. (A–E) Levels of adipocytokines in SPG11 patients compared to controls, including (A) leptin, (B) adiponectin, (C) progranulin, (D) resistin, and (E) CTRP-3. (F–H) Basal levels of cortisol (F), adrenocorticotropic hormone (ACTH, G), and thyroid-stimulating hormone (TSH, (H)) were within normal range in most patients and there was no significant difference to controls. Red data points in H indicate subjects with known thyroid function disorder. (I) Basal triglyceride levels were within normal limits in most patients and controls. Dotted lines indicate reference ranges. Bars indicate means ± SD. ns: not significant, * p < 0.05.