Table 1.
Patient characteristics.
| Parameter (Mean ± SD) |
SPG11 HSP N = 16 |
Controls N = 16 |
p Value |
|---|---|---|---|
| Age (y) | 31.1 ± 10.9 | 36.1 ± 11.6 | >0.05 |
| Gender (male: female) | 8:8 | 7:9 | >0.05 * |
| Body Mass Index (kg/m2) | 29.1 ± 4.6 | 25.0 ± 3.7 | 0.02 |
| Age of onset (y) | 12.7 ± 11.0 | --- | |
| Disease duration (y) | 18.4 ± 8.0 | --- | |
| SPRS total score | 30.2 ± 10.4 | --- | |
| SPRS functional measures | 18.4 ± 6.0 | --- | |
| (sum of items #1–#6) | |||
| SPRS spasticity measures (#7–#10) | 8.0 ± 3.3 | --- | |
| SPRS non-motor measures (#11–#13) | 3.8 ± 2.3 | --- |
* Chi-squared test, SPRS: Spastic Paraplegia Rating Scale.