Table 3.

Effect of Cervical Microbiota on ART Outcome.

Parameter	Outcome * [Reference]	No Effect Author [Reference]	Positive Correlation Author [Reference]	Negative Correlation Author [Reference]	Comments
High richness of species				Hyman et al. [54] Bernabeu et al. [55]
High diversity				Graspeuntner et al. [36] Hyman et al. [54] Haahr et al. [56] Amato et al. [57]
High % of Lactobacillus sp. **		Hyman et al. [54] Bernabeu et al. [55] Kyono et al. [34] # Wang et al. [58]	Graspeuntner et al. [36] (infectious) Kyono et al. [34] $		Different cut-off values correlate differently
L. crispatus (CST 1)		Haahr et al. [56]	Graspeuntner et al. [36] Villani et al. [59]	Koedooder et al. [60] Hao et al. [61]	Low levels in fresh ET and frozen-thawed ET favored pregnancy
L. gasseri (CST 2)		Haahr et al. [56]	Hao et al. [61]	Graspeuntner et al. [36] Hao et al. [61]	Low levels in fresh ET and high levels in frozen-thawed ET favored pregnancy
L. iners (CST 3)		Graspeuntner et al. [36]		Villani et al. [59]
L. jensenii (CST 5)		Haahr et al. [56]	Hao et al. [61]	Koedooder et al. [60] Hao et al. [61]	Low levels in fresh ET and high levels in frozen-thawed ET favored pregnancy
CST 4 (diverse bacteria) Presence of other species—No effect—Haahr et al. [56]
Bifidobacterium sp.			Villani et al. [59]
Gardnerella sp.		Kitaya et al. [51] Bernabeu et al. [55]		Koedooder et al. [60] Wee et al. [39] Graspeuntner et al. [36]
Streptococcus sp.		Bernabeu et al. [55]		Wang et al. [58]
Atopobium sp.				Villani et al. [59]
Sneathia sp.				Graspeuntner et al. [36]
Ureaplasma parvum		Bernabeu et al. [55]
Prevotella sp.				Graspeuntner et al. [36]
Clostridium		Bernabeu et al. [55]
Proteobacteria			Villani et al. [59]	Koedooder et al. [60]
Solanum torvum				Wang et al. [58]
Fusobacterium				Wang et al. [58]
Yersinia			Villani et al. [59]

sp. = Species. * All studies included pregnancy rate/implantation rate/chemical pregnancy. Thus, any additional outcomes are mentioned here. ** Cut-off ≥ 90% = #, cut-off value ≥ 80% = $.