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The effect of FAD and PLP treatment on the expression of key pancreatic progenitor transcription factors. RT-qPCR analysis of the PTF1a and NGN3 expression after treating iPSC-derived pancreatic progenitors for 24 h with FAD (A) or PLP (B). Western blot analysis for the expression of SOX9 (C) and PTF1a (D) after treating iPSC-derived pancreatic progenitors for 4 days with FAD. Data are represented as mean ± SD; ** p < 0.01, *** p < 0.001.
