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Direct effects of Cuprizone treatment on SVZ and SGZ neurosphere growth. Representative neurosphere images from different Cuprizone concentration or vehicle treatment initiated at 48-h after cell plating and harvested at 7 days after plating. Quantification of neurosphere radius shown in lower panel. The data are presented as MEAN± SEM. ***p < .001. ANOVA (n = 6 for each group). Scale bar =100um.
