Figure 7.

After incubating K562 cells with AECRs (200, 300, and 400 μg/mL) for 4 days, the expression of these proteins were determined by Western blot. These proteins were (A) IRS1, PI3K, AKT, and mTOR; (B) ESR1, RAS, MEK, and ERK; (C) JAK2 and STAT3; (D) TAL1, c-Myb, MEIS1, and and PBX1. On the right, this statistical histogram represents the protein level in each group. The values represent the means ± standard deviations (n = 3). * p < 0.05, ** p < 0.01, *** p < 0.001 versus the control group. AECRs: aqueous extracts of Cibotii rhizoma.