Table 9.
Survivability of the L. rhamnsous CA15 (DSM 33960) strain in presence of lysozyme, acidic conditions, and bile salts and during in vitro-simulated gastrointestinal transit.
| Tested Activity | Condition | Time | Survival Rate (SR%) |
|---|---|---|---|
| Lysozyme tolerance | 30 min | 95% | |
| 120 min | 93% | ||
| Tolerance to low pH | 3.0 | 2 h | 92% |
| 4 h | 86% | ||
| 2.0 | 2 h | 89% | |
| 4 h | 83% | ||
| Tolerance to bile salts | 0.5% | 2 h | 91% |
| 4 h | 87% | ||
| 1% | 2 h | 89% | |
| 4 h | 82% | ||
| Simulated GI digestion | SGJ * | 99.7% | |
| SIF ** | 95.7% |
* Simulated gastric juice; ** Simulated intestinal fluid. Survival rate (SR%) was calculated based on the initial and the final numbers of viable cells enumerated on MRS agar after 48 h.