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. 2022 Oct 31;14(11):2346. doi: 10.3390/pharmaceutics14112346

Figure 2.

Figure 2

Schematic representing structure and pH-sensitive transmembrane mechanism of pHLIP. (A) The main features of three sequences of pHLIP. (B) Schematic model of membrane interaction at physiological pH and insertion at low pH of pHLIP. Reproduced with permission [83]. Copyright 2017, Elsevier. (C) Preparation of pHLIP-modified MONs and their targeting cancer therapy by pH-triggered transmembrane behavior. Reproduced with permission [81]. Copyright 2017, American Chemical Society.

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