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Design and responsive mechanism of enzyme-triggered srNPs. (A) Illustration of recognition, transport and α-glycosidase-triggered release of prodigiosin-loaded β-cyclodextrin-MNPs at the tumor site. Reproduced with permission [128]. Copyright 2017, Elsevier. (B) Illustration of synthesis and sPLA2-triggered activation mechanism of TRAIL-loaded DNA NCs covered with liposome. Reproduced with permission [120]. Copyright 2016, Elsevier.
