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. 2022 Oct 29;14(11):2400. doi: 10.3390/v14112400

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© 2022 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Alignment of aa partial hexon protein sequences of PAdV-5 Ino5, PAdV-5 HNF-70 (AF289262), porcine adenovirus 3 (AC_000189), and Human adenovirus 3 GB strain (AY599834) (A) Structure prediction and comparison of the hexon tower region of PAdV-5 Ino5, PAdV-5 HNF-70, porcine adenovirus 3, and Human adenovirus 3 GB strain. The three-dimensional protein structures were predicted by Alphafold2 (https://colab.research.google.com/github/sokrypton/ColabFold/blob/main/AlphaFold2.ipynb accessed on 1 September 2022) and visualized in ChimeraX. The predicted 3D structure of the tower region of the hexon protein segment 3, hypervariable region in the segment 3, and segment 7 are colored by blue, red, and orange (B).