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. 2022 Oct 27;298(12):102642. doi: 10.1016/j.jbc.2022.102642

Figure 1.

Figure 1

Aβ1-42activates all human FPRs.A, representative Ca2+ traces of HEK293T cells transiently transfected with FPR plasmids or an empty vector (mock) after stimulation with Aβ1-42 obtained from P&E. B, mean peak Ca2+ responses of human (red) and mouse (blue) FPRs upon stimulation with different concentrations of Aβ1-42. Buffer (gray) denotes responses to the assay buffer without Aβ1-42. Bars represent mean values of three independent experiments (n = 3) carried out as technical duplicates (N = 2). All Error bars, S.D.; One-way ANOVA test, Dunnett post hoc test; ∗p ≤ 0.05; ∗∗p ≤ 0.01; ∗∗∗p ≤ 0.001; ns, no significance. Aβ, amyloid beta; FPR, Formyl peptide receptor.