TABLE 1.

Detection by plasmid profile analysis of predominant population members of B. burgdorferi isolate 225c in isolates from C3H mice inoculated with 225c and combinations of subclones 2E7′ and 3B6′

Inoculuma	Mouse	Presence of 2E7′/3B6′ at (weeks postinfection)b:
		3	5	27	52
225c	1	+/+	+/+	+/+	+/−
	2	−/+	−/+	−/+	−/+
	5	−/+	−/+	−/+	−/+
	55	+/+	+/+	+/−	+/+
	56	+/+	+/−	+/−	+/−
	57	Neg	+/+	+/−	+/−
	60	Neg	+/+	+/+	+/+
2E7′-3B6′ (50:50)	16	−/+	−/+	−/+	−/+
	17	−/+	+/+	+/−	−/+
	19	Neg	−/+	−/+	−/+
	41	+/−	+/−	+/−	+/−
	42	−/+	−/+	+/+	−/+
	43	+/−	−/+	+/−	−/+
2E7′-3B6′ (90:10)	31	−/+	+/−	+/−	+/+
	32	+/+	+/+	+/+	+/+
2E7′-3B6′ (10:90)	38	+/+	−/+	−/+	+/+
	52	+/+	−/+	−/+	+/+

^aMice were infected with an intradermal inoculum of 2 × 10³ spirochetes in BSK II medium. 

^bDetection (+) of plasmid profile characteristic of subclone 2E7′ indicated to the left of the slash mark and of subclone 3B6′ to the right of slash mark. 

^cNeg, culture negative.