Table 1.

SNPs and Weights in the Polygenic Risk Score Model ¹.

Term	Estimate	std.error	Statistic	p-Value	Overlapped Gene	Nearest Upstream Gene	Nearest Downstream Gene
rs1173743	0.1453	0.031	4.712	$2.45\times {10}^{-6}$	NPR3
rs4660586	−0.1570	0.034	−4.603	$4.17\times {10}^{-6}$	HIVEP3
rs77979097	0.3020	0.071	4.266	$1.99\times {10}^{-5}$	CSMD1
rs29282	0.2175	0.053	4.128	$3.66\times {10}^{-5}$	FMR1
rs144401118	0.5282	0.130	4.068	$4.75\times {10}^{-5}$		RP11-102N11.1	SMLR1
rs167479	−0.1247	0.031	−4.000	0.0001	RGL3
rs193168008	1.1161	0.282	3.965	0.0001		LINC01019	IRX1
rs534036441	0.9111	0.234	3.901	0.0001		RNU6-163P	LINC00704
rs537363408	1.0705	0.275	3.893	0.0001	RAD51B
rs190092234	1.1370	0.294	3.865	0.0001	OSBPL6
rs141667164	1.2467	0.326	3.830	0.0001		DEF6	PPARD
rs115654387	0.4269	0.112	3.811	0.0001		RP11-329N22.1	RP11-334L9.1
rs544149038	1.3523	0.360	3.753	0.0002		C14orf177	AL132796.1
rs113046103	0.2230	0.060	3.703	0.0002	SHANK2
rs561028558	1.1228	0.303	3.700	0.0002	TOP2A
rs191614564	0.4953	0.137	3.607	0.0003		SCRT2	SLC52A3
rs72674615	0.6124	0.170	3.604	0.0003	LINC00609; PTCSC3
rs113882455	0.4979	0.143	3.474	0.0005		U40455.1	RPL7L1P11
rs28558138	0.1080	0.031	3.452	0.0006		TBC1D19	STIM2
rs71519836	0.2241	0.065	3.447	0.0006		MYOM2	AC133633.2
rs80043362	0.1698	0.050	3.413	0.0006	JPH2
rs183374245	0.4377	0.129	3.400	0.0007	CACNA2D1
rs2409532	−0.0991	0.030	−3.342	0.0008	AP000330.8
rs145385264	0.2780	0.083	3.333	0.0009	RP11-344P13.4
rs558954655	0.7364	0.222	3.311	0.0009	SPON2

¹ Table with top most significant SNPs from the polygenic risk score as the result of the machine-learning procedure. SNPs are annotated using SNPnexus. Full Table with all 115 SNPs and their weights is available in the Supplementary Table S1.