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. 2022 Nov 15;99(20):e2264–e2274. doi: 10.1212/WNL.0000000000201120

Figure 3. iN Proteins and Age-Related Neuropathologies.

Figure 3

The figure illustrates the associations of iN protein expressions with common age-related neuropathologic indices. Results are presented as −log10(p) such that higher the value, more significant the association. Red color represents a positive association, and blue represents a negative association. Vertical dotted line is the reference cutoff representing p = 0.00625 (i.e., 0.05/8). ACTN4 = alpha-actinin-4; AK4 = adenylate kinase 4; CPLX1 = complexin-1; iN = induced neuron; ITPK1 = inositol-tetrakisphosphate 1-kinase; NRN1 = neuritin; SGTB = small glutamine-rich tetratricopeptide repeat-containing protein beta; SH3GL1 = endophilin-A2; UBA1 = ubiquitin-like modifier-activating enzyme 1.