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. 2022 Nov 15;99(20):e2264–e2274. doi: 10.1212/WNL.0000000000201120

Figure 5. iN Proteins and Domain-Specific Residual Cognitive Decline.

Figure 5

The figure illustrates the associations of iN protein expressions with domain-specific residual cognitive decline. Candidate proteins are on the x-axis, and measures for domain-specific residual cognitive declines are on the y-axis. Red tile represents a positive association (i.e., higher expression is associated with slower residual decline), and blue tile represents a negative association (i.e., higher expression is associated with faster residual decline). The size of black dot inside the tile signifies the strength of an association. ACTN4 = alpha-actinin-4; AK4 = adenylate kinase 4; CPLX1 = complexin-1; iN = induced neuron; ITPK1 = inositol-tetrakisphosphate 1-kinase; NRN1 = neuritin; SGTB = small glutamine-rich tetratricopeptide repeat-containing protein beta; SH3GL1 = endophilin-A2; UBA1 = ubiquitin-like modifier-activating enzyme 1.