Synergistic, additive or antagonistic effect against AgPtNPs and antibiotics (ampicillin and vancomycin). (A–C) panels clarify the synergistic effect against S. aureus ATCC, MS and MDR bacterial strain. (D−F) panels indicate the additive effect against E. faecalis ATCC, MS and MDR bacterial strains. (G–I) panels indicate the synergistic effect against E. coli ATCC, MS and MDR bacterial strains. Lastly, (J–L) panels indicate the additive and synergistic effects against K. pneumoniae ATCC, MS and MDR bacterial strain. NP: nanoparticles; Ab: antibiotic. Data are means of three independent experiments. Significant diff. among means **: p < 0.01.