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. 2022 Nov 25;10(12):e748. doi: 10.1002/iid3.748

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© 2022 The Authors. Immunity, Inflammation and Disease published by John Wiley & Sons Ltd.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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(A) The reaction of the recP1, recP2, and recN antigenic proteins with 1/100 diluted sera was obtained from recovered COVID‐19 patients in ELISA tests. (B) Binding activity between P1 (containing RBD) fragment protein and ACE2. Statistically significant(p < .05) increase compared to the control was shown with an asterisk. One‐way ANOVA followed by Dunnett's multiple comparisons test was used for statistical analysis. ACE2, angiotensin‐converting enzyme 2; ANOVA, analysis of variance; COVID‐19, coronavirus disease 19; ELISA, enzyme‐linked immunosorbent assays; RBD, receptor‐binding domain.