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. 2022 Oct 31;10(11):1849. doi: 10.3390/vaccines10111849

Figure 2.

Figure 2

Schematic diagram of COVID-19 synthetic DNA and RNA vaccine constructs. Schematic diagram of COVID-19 synthetic DNA vaccine constructs (left), where plasmids containing the IgE leader sequence and SARS-CoV-2 spike protein insert are shown. Schematic diagram of COVID-19 synthetic RNA vaccine constructs (right), showing the S1 (N-terminal furin cleavage fragment), S2 (C-terminal furin cleavage fragment), and RBD (receptor-binding domain). The positions of the P2 mutation (K986P and V987P) are indicated.