Table 2.

The common adverse reactions to COVID-19 nucleic acid vaccines.

Vaccine Name	Common Local Adverse Reactions	Common Systemic Adverse Reactions	Serious Adverse Events
ZyCoV-D	pain, redness, swelling, and itching	headache, fever, muscle pain, and fatigue	cerebrovascular stroke, cardiorespiratory arrest with septicaemia, and alcoholic liver disease
INO-4800	pain and erythema	nausea	none currently reported
BNT162b2	pain, redness, and swelling	fatigue, headache, chills, and muscle pain	hypersensitivity reaction, paroxysmal ventricular arrhythmia, and death
mRNA-1273	pain, erythema, swelling, and lymphadenopathy	fatigue, headache, myalgia, and arthralgia	hypersensitivity reactions, Bell’s palsy, and death