Table 3.
Regression 1* | Regression 2† | |||||||
---|---|---|---|---|---|---|---|---|
Single-Time (67 Eyes) | Multiple-Times (30 Eyes) | B | OR (95%CI) | P | B | OR (95%CI) | P | |
Sex | ||||||||
Female | 44 (65.7%) | 23 (76.7%) | Ref. | Ref. | — | Ref. | — | |
Male | 23 (34.3%) | 7 (23.3%) | −0.568 | 0.567 (0.135, 2.066) | 0.408 | −0.506 | 0.603 (0.143, 2.209) | 0.462 |
Age (y), mean (SD) | 66.5 (12.7) | 67.4 (9.9) | 0.054 | 1.055 (0.990, 1.133) | 0.112 | 0.065 | 1.067 (0.999, 1.150) | 0.066 |
Axial length (mm), mean (SD) | 30.55 (2.26) | 31.41 (1.83) | 0.554 | 1.741 (1.172, 2.802) | 0.012* | 0.622 | 1.863 (1.223, 3.112) | 0.009† |
IOP (mm Hg), mean (SD) | 14.91 (3.56) | 15.32 (2.86) | — | — | — | — | ||
Refractive error (D), mean (SD) | −14.85 (4.81) | −15.56 (7.57) | — | — | — | — | ||
Median BCVA [25%; 75%] | 0.70 [0.25; 0.90] | 0.90 [0.12; 1.00] | 0.308 | 1.360 (0.361, 4.940) | 0.635 | 0.408 | 1.504 (0.350, 6.065) | 0.566 |
Median absorption period (d), [25%; 75%] | 185.50 [126.00; 313.25] | 182.00 [126.00; 371.00] | — | — | — | — | ||
Category of myopic maculopathy‡, eyes | 0.098 | 0.034 | ||||||
Diffuse atrophy (C2) | 21 (31.3%) | 14 (46.7%) | Ref. | Ref. | — | Ref. | — | |
Patchy atrophy (C3) | 33 (49.3%) | 9 (30.0%) | −1.669 | 0.188 (0.036, 0.796) | 0.031* | −2.158 | 0.116 (0.019, 0.526) | 0.009† |
Macular atrophy (C4) | 13 (19.4%) | 7 (23.3%) | −2.040 | 0.130 (0.011, 1.125) | 0.080 | −3.279 | 0.038 (0.001, 0.500) | 0.027† |
Possible ON damage | 11 (16.4%) | 12 (40.0%) | 1.366 | 3.920 (1.152, 14.506) | 0.032* | |||
Possible glaucoma | 4 (6.0%) | 5 (16.7%) | 2.362 | 10.617 (1.578, 98.313) | 0.022† |
B, regression coefficient; Ref, reference; SD, standard deviation.
Multivariate binary regression analysis included sex, age, axial length, BCVA and category of myopic maculopathy, possible ON damage.
Multivariate binary regression analysis included sex, age, axial length, BCVA and category of myopic maculopathy, possible glaucoma.
According to META-PM study classification.