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. 2022 Oct 25;15(11):1317. doi: 10.3390/ph15111317

Table 3.

The molecular descriptor and parameters of Lipinski’s, Ghose’s, and Veber’s rules for palmatine (1), metformin (2) & glimepiride (3) data here.

No Molecular Mass (M) H-Bond Acceptors H-Bond Donors Rotatable Bonds TPSA LogP
Consensus
Lipinski’s
Rules
Ghose’s
Rules
Veber’s
Rules
Muegge’s
Rules
1 352 4 0 4 40.80 2.64 + + + +
2 129 3 2 4 36.93 0.75 + - + -
3 490 11 5 3 133 2.76 + - - +