Table 2.
Formulation Code | Zero-Order | First-Order | Hixson-Crowell | Higuchi | Korsmeyer-Peppas | |
---|---|---|---|---|---|---|
r2 | r2 | r2 | r2 | r2 | n | |
Pr-QCT-SLNs-7 | 0.901 | 0.995 | 0.995 | 0.975 | 0.997 | 0.60 |
Pr-QCT-SLNs-8 | 0.909 | 0.996 | 0.997 | 0.967 | 0.998 | 0.82 |
Pr-QCT-SLNs-9 | 0.901 | 0.998 | 0.995 | 0.964 | 0.998 | 0.62 |
C-Pr-QCT-SLNs-8 | 0.868 | 0.981 | 0.962 | 0.979 | 0.995 | 0.68 |
St-QCT-SLNs-2 | 0.890 | 0.993 | 0.997 | 0.971 | 0.998 | 0.78 |
C-St-QCT-SLNs-2 | 0.860 | 0.996 | 0.997 | 0.967 | 0.999 | 0.81 |
Abbreviations: QCT: quercetin, Pr: precirol, St: stearic acid, C: coated, SLNs: solid lipid nanoparticles. The numbers 7,8 and 9 donate lipid to drug ratios 5:1, 10:1 and 15:1 respectively.