Table 3.

Supercritical-Fluid Extraction for bioactive compounds from macroalgae, extraction parameters, bioactive compounds targeted, and extraction yield.

Macroalgae	Extraction Parameters					Bioactive Compounds	Bioactivity	Extraction Yield (%)	Reference
	Solvent (v/v)	Temperature (°C)	Pressure (MPa)	Extraction Time (min)	CO2 Flow Rate
S. japonica	CO2:EtOH	45	25	120	27 g/min	Fucoxanthin	Antioxidant	1.09 ± 0.56 a	[10]
S. horneri							Antimicrobial	1.41 ± 0.15 a
U. pinnatifida	CO2	25	40	180	2 mL/min	Fucoxanthin	---	0.53 ± 0.05	[65]
		40	40					1.22 ± 0.04
		40	20					1.08 ± 0.02
		40	30					1.06 ± 0.03
		50	40					1.07 ± 0.01
		60	40					1.04 ± 0.01
L. japonica	Sunflower oil, soybean oil, canola oil, EtOH, H2O	45	20	240	---	Carotenoids	Antioxidant	See Table 4	[66]
		50	25			Fucoxanthin
		55	30			Phlorotannins

a: g/100 g DW.